2
Why does the liver enlarge in thalassemia?
- 1 people answered
3 Votes
1 Contributor
3396 Views 
0 Saved
3 Votes 1 Contributor3396 Views 0 SavedYou might also be interested in
A fatty liver disease can be occurred due to alcoholism which results in the production of toxic metabolites like aldehydes during metabolism of alcohol in the liver, commonly occurs with chronic alcoholism. A fatty liver disease can also be occurred due to heavy drinking, obesity, hyperlipidemia, h....
There is a misunderstanding that eating fish or meat the increased risk of developing hepatic encephalopathy in the patient with liver cirrhosis. Fish contain essential fatty acids in their natural and unprocessed form. Wild fish should be proffered instead of farmed fishes. Fishes like Sardines, ki....
For liver enlargement, Hepatologist should be consulted.Because hepatologist is the most experienced and qualified doctors who treat people with liver disease. But there is no separate central board certification examination in this specialized field. Though there are some specific training programs....
Akanksha Pardeshi
The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.